Expression of USP18 and IL2RA Is Increased in Individuals Receiving Latent Tuberculosis Treatment with Isoniazid
نویسندگان
چکیده
منابع مشابه
Evaluation of Interleukin17and Interleukin 23 expression in patients with active and latent tuberculosis infection
Objective(s): Tuberculosis is one of the most important infectious diseases with high mortality rates worldwide, especially in developing countries. Interleukin17 (IL-17) is an important acquired immunity cytokine, which is mainly produced by CD4+TH17 cells. It can recruit neutrophils and macrophages to the infected site in the lungs. IL-23 is one of the most important inducers of IL-17. In the...
متن کاملAntepartum or postpartum isoniazid treatment of latent tuberculosis infection.
OBJECTIVE To compare health outcomes and costs of different strategies for treatment of latent tuberculosis infection in pregnancy. METHODS Using a Markov decision-analysis model, the following three strategies were evaluated for treatment of latent tuberculosis infection in pregnancy, defined as positive tuberculin skin reaction of 10 mm or greater and negative chest radiograph: no treatment...
متن کاملMonitoring toxicity in individuals receiving treatment for latent tuberculosis infection: a systematic review versus expert opinion
Latent tuberculosis infection (LTBI) is defined as a state of persistent immune response to stimulation by Mycobacterium tuberculosis antigens without evidence of clinically manifested active TB [1]. The World Health Organization (WHO) estimates that one-third of the global population is infected by Mycobacterium tuberculosis [2]. They cannot transmit tuberculosis (TB), but they can develop the...
متن کاملManagement of Latent Tuberculosis in Iran
Although screening, finding and treatment of active cases of tuberculosis is very important for control of disease in the community, for reaching to the goals planed by world health organization and approaching to elimination of the disease, it is necessary to find and treat persons with latent infection. Concerning to high prevalence of latent TB in developing countries and resource limitation...
متن کاملThree months of rifapentine and isoniazid for latent tuberculosis infection.
BACKGROUND Treatment of latent Mycobacterium tuberculosis infection is an essential component of tuberculosis control and elimination. The current standard regimen of isoniazid for 9 months is efficacious but is limited by toxicity and low rates of treatment completion. METHODS We conducted an open-label, randomized noninferiority trial comparing 3 months of directly observed once-weekly ther...
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ژورنال
عنوان ژورنال: Journal of Immunology Research
سال: 2019
ISSN: 2314-8861,2314-7156
DOI: 10.1155/2019/1297131